iPTMnet Report for P07203 (GPX1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P07203 / GPX1_HUMAN
Protein Name Glutathione peroxidase 1
Gene Name Name: GPX1
Organism Homo sapiens (Human)

PRO ID PR:P07203
DAG View
PRO Name glutathione peroxidase 1 (human)
Definition A glutathione peroxidase 1 that is encoded in the genome of human.
Short Label hGPX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P07203 (GPX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S34 Phosphorylation PhosphoSitePlus
K88 Acetylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
Y98 Phosphorylation neXtProt   PhosphoSitePlus   Signor 12893824
Y98 Phosphorylation P00519 (ABL1) neXtProt   PhosphoSitePlus   Signor 12893824
Y98 Phosphorylation P42684 (ABL2) neXtProt   PhosphoSitePlus   Signor 12893824
T145 Phosphorylation PhosphoSitePlus
K148 Acetylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus   UniProt 24275569
C202 S-Nitrosylation dbSNO 26338901
Site PTM Type PTM Enzyme Score Source PMID
Y98 Phosphorylation HPRD 12893824
Y98 Phosphorylation P00519 (ABL1) HPRD 12893824
Y98 Phosphorylation P42684 (ABL2) HPRD 12893824


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K88 N88 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K148 E148 Biomuta DOID:5041 / esophageal cancer [ cosmic ]