Protein Information

Cytoscape View

UniProt AC / UniProt ID P07203 / GPX1_HUMAN
Protein Name Glutathione peroxidase 1
Gene Name Name: GPX1
Organism Homo sapiens (Human)

PRO ID PR:P07203
DAG View
PRO Name glutathione peroxidase 1 (human)
Definition A glutathione peroxidase 1 that is encoded in the genome of human.
Short Label hGPX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P07203 (GPX1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S34 Phosphorylation PhosphoSitePlus
K88 Acetylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
Y98 Phosphorylation P42684 (ABL2) , P00519 (ABL1) neXtProt   PhosphoSitePlus   Signor 12893824
T145 Phosphorylation PhosphoSitePlus
K148 Acetylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus   UniProt 24275569
C202 S-Nitrosylation dbSNO 26338901
Site PTM Type PTM Enzyme Score Source PMID
Y98 Phosphorylation P42684 (ABL2) , P00519 (ABL1) HPRD 12893824

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K88 N88 Biomuta DOID:363 / uterine cancer [ tcga ]
K148 E148 Biomuta DOID:5041 / esophageal cancer [ icgc ]
S180 N180 Biomuta DOID:1793 / pancreatic cancer [ tcga ]