Protein Information

Cytoscape View

UniProt AC / UniProt ID P06240 / LCK_MOUSE
Protein Name Proto-oncogene tyrosine-protein kinase LCK
Gene Name Name: Lck
Organism Mus musculus (Mouse)

PRO ID PR:P06240
DAG View
PRO Name proto-oncogene tyrosine-protein kinase LCK (mouse)
Definition A tyrosine-protein kinase Lck that is encoded in the genome of mouse.
Short Label mLCK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P06240 (Lck) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 7980442
S35 Phosphorylation PRO   PhosphoSitePlus 21183079
S42 Phosphorylation PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus   RLIMS-P 8258696, 8077654
Y192 Phosphorylation PRO   PhosphoSitePlus   UniProt 21183079
Y394 Phosphorylation P06240 (Lck) PhosphoSitePlus   RLIMS-P 1594248, 22523384, 11294838, ...29073235, 9658584, 2118992, 2250907, 18981123, 1311128, 8756658, 9973453
T395 Phosphorylation PhosphoSitePlus
Y505 Phosphorylation P41241 (Csk) , P06240 (Lck) PhosphoSitePlus   RLIMS-P 15743820, 22523384, 16446380, ...11847223, 9658584, 25595912, 17277109, 8413300, 8441403, 8756658, 9973453

P06240 (Lck) as PTM Enzyme

Substrate Site Score Source PMID
P06240 (Lck) Y394 PhosphoSitePlus 1311128
P06240 (Lck) Y505 PhosphoSitePlus 11847223
P09793 (Ctla4) Y201 phospho.ELM   PhosphoSitePlus 9973379
P09793 (Ctla4) Y218 phospho.ELM   PhosphoSitePlus 9973379
P27870 (Vav1) Y142 phospho.ELM 10669745
P27870 (Vav1) Y160 phospho.ELM 10669745
P27870 (Vav1) Y174 phospho.ELM 10669745
P28867 (Prkcd) Y311 phospho.ELM 11381116
P29351 (Ptpn6) Y536 Signor 8114715
P43404 (Zap70) Y318 Signor 10037717
P63085 (Mapk1) Y185 PhosphoSitePlus 1311128
Q03526 (Itk) Y517 PhosphoSitePlus 12842872
Q08481 (Pecam1) Y679 phospho.ELM   PhosphoSitePlus 9624175
Q08481 (Pecam1) Y702 PhosphoSitePlus 9624175
Q9EQR5 (Lime1) Y242 PhosphoSitePlus 14610044
Q9EQR5 (Lime1) Y261 PhosphoSitePlus 14610044
Q9ES52 (Inpp5d) Y918 PhosphoSitePlus 9099679
Q9ES52 (Inpp5d) Y1021 PhosphoSitePlus 9099679


PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049824 (mLCK/Phos:2) pS35 PRO 21183079
PR:000049825 (mLCK/Phos:3) pY192 PRO 21183079