iPTMnet Report P02748 C9

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P02748 / CO9_HUMAN
Protein Name	Complement component C9 precursor
Gene Name	Name: C9
Organism	Homo sapiens (Human)

PRO ID	PR:P02748 DAG View
PRO Name	complement component C9 (human)
Definition	A complement component C9 that is encoded in the genome of human.
Short Label	hC9
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P02748 (C9) as Substrate

Condensed View

Search:

	Site Select all By amino acid All Serine All Threonine All Tyrosine By position T24 S26 T32 W48 W51 S66 N123 K225 T244 T248 T258 S261 N277 T316 Y383 S392 S395 N415 K435	PTM Type Select all C-Glycosylation N-Glycosylation O-Glycosylation Phosphorylation Ubiquitination	PTM Enzyme Select all	Score Select all 0 1 3 4	Source Select all GlyGen HPRD PhosphoSitePlus UniProt	PMID
	T24	O-Glycosylation		score1	GlyGen	30459171
	S26	O-Glycosylation		score1	GlyGen	30459171
	T32	O-Glycosylation		score1	GlyGen	30459171
	W48	C-Glycosylation		score3	GlyGen UniProt	10551839
	W51	C-Glycosylation		score3	GlyGen UniProt	10551839
	S66	Phosphorylation		score1	PhosphoSitePlus
	N123	N-Glycosylation		score1	GlyGen	23090970
	K225	Ubiquitination		score1	PhosphoSitePlus
	T244	Phosphorylation		score1	PhosphoSitePlus
	T248	Phosphorylation		score1	PhosphoSitePlus
	T258	O-Glycosylation		score1	GlyGen	30459171
	S261	Phosphorylation		score0	HPRD	19824718
	N277	N-Glycosylation		score4	GlyGen UniProt	16335952, 19159218, 23090970, ...29671580, 29741879, 4055801
	T316	Phosphorylation		score0	HPRD	20068231
	Y383	Phosphorylation		score1	PhosphoSitePlus
	S392	Phosphorylation		score1	PhosphoSitePlus
	S395	Phosphorylation		score1	PhosphoSitePlus
	N415	N-Glycosylation		score4	GlyGen UniProt	16335952, 19159218, 23090970, ...29671580, 14760718, 29391424, 16263699, 19139490, 29741879, 4055801
	K435	Ubiquitination		score1	PhosphoSitePlus

Search:

	Site Select all By amino acid By position N277 N415	PTM Type Select all N-Glycosylation	PTM Enzyme Select all	Score Select all 1	Source Select all PRO	PMID
	N277	N-Glycosylation		score1	PRO	29671580
	N415	N-Glycosylation		score1	PRO	29671580

PTM sites affected in variants

Search:

Site Select all By amino acid All Serine All Threonine By position T24 S26 W48 W51 S66 N123 K225 T258 S395 K435	Variant Select all * A258 C26 D123 F395 I225 M24 Q435 R66	Source Select all Biomuta	PMID	Disease [Sample source] Select all DOID:1324 / lung cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1793 / pancreatic cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T24	M24	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
S26	C26	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
W48	*	Biomuta		DOID:4159 / skin cancer [ cosmic ]
W51	*	Biomuta		DOID:1324 / lung cancer [ cosmic ]
S66	R66	Biomuta		DOID:1793 / pancreatic cancer [ cosmic ]
N123	D123	Biomuta		DOID:363 / uterine cancer [ cosmic, icgc ]
K225	I225	Biomuta		DOID:1324 / lung cancer [ cosmic, icgc ]
T258	A258	Biomuta		DOID:4159 / skin cancer [ cosmic ]
S395	F395	Biomuta		DOID:4159 / skin cancer [ cosmic ]
K435	Q435	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]