Protein Information

Cytoscape View

UniProt AC / UniProt ID P02748 / CO9_HUMAN
Protein Name Complement component C9 precursor
Gene Name Name: C9
Organism Homo sapiens (Human)

PRO ID PR:P02748
DAG View
PRO Name complement component C9 (human)
Definition A complement component C9 that is encoded in the genome of human.
Short Label hC9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P02748 (C9) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
W48 C-Glycosylation UniProt 10551839
W51 C-Glycosylation UniProt 10551839
S66 Phosphorylation PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
T244 Phosphorylation PhosphoSitePlus
T248 Phosphorylation PhosphoSitePlus
S261 Phosphorylation HPRD 19824718
N277 N-Glycosylation UniProt 16335952, 4055801, 19159218
T316 Phosphorylation HPRD 20068231
Y383 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
N415 N-Glycosylation UniProt 16335952, 19159218, 14760718, ...16263699, 19139490, 4055801
K435 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
W48 * Biomuta DOID:1909 / melanoma [ icgc, tcga ]
W51 * Biomuta DOID:1324 / lung cancer [ tcga ]
S66 R66 Biomuta DOID:1324 / lung cancer [ tcga ] DOID:0070003 / blastoma [ cosmic ]
K225 I225 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
K435 Q435 Biomuta DOID:1909 / melanoma [ cosmic ]