iPTMnet Report for P01308 (INS)
Protein Information
| UniProt AC / UniProt ID | P01308 / INS_HUMAN |
| Protein Name | Insulin precursor |
| Gene Name | Name: INS |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P01308 |
| PRO Name | insulin gene translation product (human) |
| Definition | An insulin gene translation product that is encoded in the genome of human. |
| Short Label | hINS |
| Category | organism-gene |
DAG ViewP01308 (INS) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S98 | Phosphorylation | score0 | RLIMS-P | 28181734 | ||
| Y108 | Phosphorylation | score1 | PhosphoSitePlus |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | P47196 (Akt1) | T308 | P01308 (INS) | unknown | eFIP | 33921370 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S98 | R98 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| Y108 | N108 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
