iPTMnet Report for P01308 (INS)
Protein Information
UniProt AC / UniProt ID | P01308 / INS_HUMAN |
Protein Name | Insulin precursor |
Gene Name | Name: INS |
Organism | Homo sapiens (Human) |
PRO ID | PR:P01308 |
PRO Name | insulin gene translation product (human) |
Definition | An insulin gene translation product that is encoded in the genome of human. |
Short Label | hINS |
Category | organism-gene |
P01308 (INS) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S98 | Phosphorylation | score0 | RLIMS-P | 28181734 | ||
Y108 | Phosphorylation | score1 | PhosphoSitePlus |
PTM-dependent PPI
PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
---|---|---|---|---|---|---|---|
Phosphorylation | P47196 (Akt1) | T308 | P01308 (INS) | unknown | eFIP | 33921370 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S98 | R98 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y108 | N108 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |