iPTMnet Report for P01133 (EGF)
Protein Information
| UniProt AC / UniProt ID | P01133 / EGF_HUMAN |
| Protein Name | Pro-epidermal growth factor precursor |
| Gene Name | Name: EGF |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P01133 |
| PRO Name | pro-epidermal growth factor (human) |
| Definition | A pro-epidermal growth factor that is encoded in the genome of human. |
| Short Label | hEGF |
| Category | organism-gene |
DAG ViewP01133 (EGF) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N104 | N-Glycosylation | score1 | GlyGen | 29741879, 32125861 | ||
| S262 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K278 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K296 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S348 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T801 | O-Glycosylation | score1 | GlyGen | 22171320 | ||
| S807 | O-Glycosylation | score1 | GlyGen | 22171320 | ||
| S954 | O-Glycosylation | score1 | GlyGen | 22171320 | ||
| T955 | O-Glycosylation | score1 | GlyGen | 22171320 | ||
| Y992 | Phosphorylation | score0 | RLIMS-P | 27796308 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S262 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| K278 | N278 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S954 | Y954 | Biomuta | DOID:363 / uterine cancer [ cosmic ] |
