Protein Information

Cytoscape View

UniProt AC / UniProt ID P01133 / EGF_HUMAN
Protein Name Pro-epidermal growth factor precursor
Gene Name Name: EGF
Organism Homo sapiens (Human)

PRO ID PR:P01133
DAG View
PRO Name pro-epidermal growth factor (human)
Definition A pro-epidermal growth factor that is encoded in the genome of human.
Short Label hEGF
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P01133 (EGF) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
N104 N-Glycosylation GlyGen 29741879, 32125861
S262 Phosphorylation PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
T801 O-Glycosylation GlyGen 22171320
S807 O-Glycosylation GlyGen 22171320
S954 O-Glycosylation GlyGen 22171320
T955 O-Glycosylation GlyGen 22171320
Y992 Phosphorylation RLIMS-P 27796308

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S262 * Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S954 Y954 Biomuta DOID:363 / uterine cancer [ cosmic ]