iPTMnet Report for P01112 (HRAS)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P01112 / RASH_HUMAN
Protein Name GTPase HRas precursor
Gene Name Name: HRAS
Synonyms:HRAS1;
Organism Homo sapiens (Human)

PRO ID PR:P01112
DAG View
PRO Name GTPase HRas (human)
Definition A GTPase HRas that is encoded in the genome of human.
Short Label hHRAS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P01112 (HRAS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Methylation PhosphoSitePlus
Y32 Phosphorylation P12931 (SRC) PhosphoSitePlus   RLIMS-P   Signor 25157176, 36458814
T35 O-Glycosylation GlyGen   UniProt 36580660, 9632667, 22665487, ...8626575, 19744486, 8626586
T35 Phosphorylation phospho.ELM   PhosphoSitePlus 9264402
S39 Phosphorylation PhosphoSitePlus
Y40 Phosphorylation PhosphoSitePlus
Y64 Phosphorylation P12931 (SRC) PhosphoSitePlus 25157176
C80 S-Nitrosylation dbSNO 24105792
Y96 Phosphorylation P12931 (SRC) PhosphoSitePlus 25157176
K117 Ubiquitination PhosphoSitePlus
C118 S-Nitrosylation dbSNO 24105792, 9020151
Y137 Phosphorylation P00519 (ABL1) , P42684 (ABL2) PhosphoSitePlus 25999467
T144 Phosphorylation P49841 (GSK3B) PhosphoSitePlus 22494971
S145 Phosphorylation PhosphoSitePlus
K147 Methylation PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
T148 Phosphorylation P49841 (GSK3B) PhosphoSitePlus 22494971
Y157 Phosphorylation PhosphoSitePlus
T158 Phosphorylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus   UniProt 30442762
C181 S-Nitrosylation dbSNO 24105792
S183 Phosphorylation PhosphoSitePlus
S189 Farnesylation IntAct 11335720
Site PTM Type PTM Enzyme Score Source PMID
S136 Phosphorylation HPRD 20068231
S145 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S136 Phosphorylation HPRD 20068231
S145 Phosphorylation HPRD 20068231


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P04049 (RAF1) S43 P01112 (HRAS) decreased_association eFIP 9001246