iPTMnet Report for P00742 (F10)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P00742 / FA10_HUMAN
Protein Name Coagulation factor X precursor
Gene Name Name: F10
Organism Homo sapiens (Human)

PRO ID PR:P00742
DAG View
PRO Name coagulation factor X (human)
Definition A coagulation factor X that is encoded in the genome of human.
Short Label hF10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P00742 (F10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T188 O-Glycosylation GlyGen 30459171, 22171320
S189 O-Glycosylation GlyGen 22171320
S190 O-Glycosylation GlyGen 22171320
S197 O-Glycosylation GlyGen 22171320
T199 O-Glycosylation GlyGen   UniProt 8243461, 22171320
Y203 O-Glycosylation GlyGen 22171320
T211 O-Glycosylation GlyGen   UniProt 8243461, 23677006
N221 N-Glycosylation GlyGen 7620335, 8243461
N231 N-Glycosylation GlyGen 7620335, 8243461
Y384 Phosphorylation PhosphoSitePlus
Y407 Phosphorylation PhosphoSitePlus
S476 O-Glycosylation GlyGen 22171320
T483 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 22171320
S484 O-Glycosylation GlyGen 22171320
S485 O-Glycosylation GlyGen 22171320
Site PTM Type PTM Enzyme Score Source PMID
N221 N-Glycosylation PRO 7620335
N231 N-Glycosylation PRO 7620335


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S190 R190 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
N221 S221 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y407 H407 Biomuta DOID:9256 / colorectal cancer [ cosmic ]