iPTMnet Report P00742 F10

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P00742 / FA10_HUMAN
Protein Name	Coagulation factor X precursor
Gene Name	Name: F10
Organism	Homo sapiens (Human)

PRO ID	PR:P00742 DAG View
PRO Name	coagulation factor X (human)
Definition	A coagulation factor X that is encoded in the genome of human.
Short Label	hF10
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P00742 (F10) as Substrate

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T188	O-Glycosylation		score1	GlyGen	30459171, 22171320
	S189	O-Glycosylation		score1	GlyGen	22171320
	S190	O-Glycosylation		score1	GlyGen	22171320
	S197	O-Glycosylation		score1	GlyGen	22171320
	T199	O-Glycosylation		score4	GlyGen UniProt	8243461, 22171320
	Y203	O-Glycosylation		score1	GlyGen	22171320
	T211	O-Glycosylation		score4	GlyGen UniProt	8243461, 23677006
	N221	N-Glycosylation		score3	GlyGen	7620335, 8243461
	N231	N-Glycosylation		score3	GlyGen	7620335, 8243461
	Y384	Phosphorylation		score1	PhosphoSitePlus
	Y407	Phosphorylation		score1	PhosphoSitePlus
	S476	O-Glycosylation		score1	GlyGen	22171320
	T483	O-Glycosylation		score2	GlyGen PhosphoSitePlus	23584533, 22171320
	S484	O-Glycosylation		score1	GlyGen	22171320
	S485	O-Glycosylation		score1	GlyGen	22171320

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N221	N-Glycosylation		score2	PRO	7620335
	N231	N-Glycosylation		score2	PRO	7620335

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S190	R190	Biomuta		DOID:1324 / lung cancer [ cosmic, icgc ]
N221	S221	Biomuta		DOID:1324 / lung cancer [ cosmic, icgc ]
Y407	H407	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]