iPTMnet Report for P00740 (F9)
Protein Information
| UniProt AC / UniProt ID | P00740 / FA9_HUMAN |
| Protein Name | Coagulation factor IX precursor |
| Gene Name | Name: F9 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P00740 |
| PRO Name | coagulation factor IX (human) |
| Definition | A coagulation factor IX that is encoded in the genome of human. |
| Short Label | hF9 |
| Category | organism-gene |
DAG ViewP00740 (F9) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T85 | O-Glycosylation | score3 | GlyGen UniProt | 25456591 | ||
| S99 | O-Glycosylation | score3 | GlyGen | 2129367, 25456591, 2511201 | ||
| S107 | O-Glycosylation | score3 | GlyGen | 8329384, 1517205, 25456591 | ||
| S114 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | |||
| S204 | Phosphorylation | score4 | PhosphoSitePlus UniProt | 11133752, 25456591 | ||
| T205 | O-Glycosylation | score4 | GlyGen UniProt | 8172892, 25456591 | ||
| T205 | Phosphorylation | score2 | UniProt | 25456591 | ||
| T215 | O-Glycosylation | score4 | GlyGen UniProt | 8172892, 25456591 | ||
| T218 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T225 | O-Glycosylation | score3 | GlyGen UniProt | 25456591 | ||
| C268 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S114 | Y114 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S204 | Y204 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| T225 | S225 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
