iPTMnet Report for P00740 (F9)
Protein Information
UniProt AC / UniProt ID | P00740 / FA9_HUMAN |
Protein Name | Coagulation factor IX precursor |
Gene Name | Name: F9 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P00740 |
PRO Name | coagulation factor IX (human) |
Definition | A coagulation factor IX that is encoded in the genome of human. |
Short Label | hF9 |
Category | organism-gene |
P00740 (F9) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T85 | O-Glycosylation | score3 | GlyGen UniProt | 25456591 | ||
S99 | O-Glycosylation | score3 | GlyGen | 2129367, 25456591, 2511201 | ||
S107 | O-Glycosylation | score3 | GlyGen | 8329384, 1517205, 25456591 | ||
S114 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | |||
S204 | Phosphorylation | score4 | PhosphoSitePlus UniProt | 11133752, 25456591 | ||
T205 | O-Glycosylation | score4 | GlyGen UniProt | 8172892, 25456591 | ||
T205 | Phosphorylation | score2 | UniProt | 25456591 | ||
T215 | O-Glycosylation | score4 | GlyGen UniProt | 8172892, 25456591 | ||
T218 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
T225 | O-Glycosylation | score3 | GlyGen UniProt | 25456591 | ||
C268 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S114 | Y114 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S204 | Y204 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T225 | S225 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |