Protein Information

Cytoscape View

UniProt AC / UniProt ID O96020 / CCNE2_HUMAN
Protein Name G1/S-specific cyclin-E2
Gene Name Name: CCNE2
Organism Homo sapiens (Human)

PRO ID PR:O96020
DAG View
PRO Name G1/S-specific cyclin-E2 (human)
Definition A G1/S-specific cyclin-E2 that is encoded in the genome of human.
Short Label hCCNE2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O96020 (CCNE2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S17 Phosphorylation PhosphoSitePlus
T19 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S21 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
K31 Ubiquitination PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
T74 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus   UniProt 18691976
T392 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18691976, 9840943, 19084516
S396 Phosphorylation PhosphoSitePlus   RLIMS-P 19084516
Site PTM Type PTM Enzyme Score Source PMID
T19 Phosphorylation HPRD 18669648
S21 Phosphorylation HPRD 19413330, 18691976, 18669648, ...20068231
S63 Phosphorylation HPRD 18691976
S383 Phosphorylation HPRD 18691976
T392 Phosphorylation HPRD 18691976, 9840943
S396 Phosphorylation HPRD 18691976

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T19 M19 Biomuta DOID:3371 / chondrosarcoma [ cosmic ]
T19 A19 Biomuta DOID:3070 / malignant glioma [ cosmic, icgc, tcga ]
S67 G67 Biomuta DOID:363 / uterine cancer [ tcga ]
T74 K74 Biomuta DOID:3571 / liver cancer [ icgc ]
T392 K392 Biomuta DOID:3571 / liver cancer [ icgc ]