iPTMnet Report for O96006 (ZBED1)
Protein Information
UniProt AC / UniProt ID | O96006 / ZBED1_HUMAN |
Protein Name | E3 SUMO-protein ligase ZBED1 |
Gene Name | Name: ZBED1 Synonyms:ALTE,DREF; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O96006 |
PRO Name | E3 SUMO-protein ligase ZBED1 (human) |
Definition | An E3 SUMO-protein ligase ZBED1 that is encoded in the genome of human. |
Short Label | hZBED1 |
Category | organism-gene |
O96006 (ZBED1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S5 | Phosphorylation | score1 | PhosphoSitePlus | |||
S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
K14 | Ubiquitination | score1 | PhosphoSitePlus | |||
K43 | Ubiquitination | score1 | PhosphoSitePlus | |||
K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
K96 | Ubiquitination | score1 | PhosphoSitePlus | |||
K98 | Ubiquitination | score1 | PhosphoSitePlus | |||
K113 | Ubiquitination | score1 | PhosphoSitePlus | |||
K154 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y167 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19664994 | ||
T170 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19664994 | ||
K171 | Ubiquitination | score1 | PhosphoSitePlus | |||
K176 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y210 | Phosphorylation | score1 | PhosphoSitePlus | |||
T212 | Phosphorylation | score1 | PhosphoSitePlus | |||
S227 | Phosphorylation | score1 | PhosphoSitePlus | |||
T268 | Phosphorylation | score1 | PhosphoSitePlus | |||
T269 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y271 | Phosphorylation | score1 | PhosphoSitePlus | |||
K273 | Ubiquitination | score1 | PhosphoSitePlus | |||
C290 | Methylation | score1 | IEDB | 31844290 | ||
K317 | Acetylation | score1 | PhosphoSitePlus | |||
K453 | Ubiquitination | score1 | PhosphoSitePlus | |||
K502 | Ubiquitination | score1 | PhosphoSitePlus | |||
K509 | Ubiquitination | score1 | PhosphoSitePlus | |||
K519 | Ubiquitination | score1 | PhosphoSitePlus | |||
K530 | Ubiquitination | score1 | PhosphoSitePlus | |||
S536 | Phosphorylation | score1 | PhosphoSitePlus | |||
T537 | Phosphorylation | score1 | PhosphoSitePlus | |||
S542 | Phosphorylation | score1 | PhosphoSitePlus | |||
K579 | Ubiquitination | score1 | PhosphoSitePlus | |||
K607 | Ubiquitination | score1 | PhosphoSitePlus | |||
K632 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K96 | M96 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
K113 | R113 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
Y167 | H167 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T170 | N170 | Biomuta | DOID:4159 / skin cancer [ icgc ] | |
K176 | N176 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
T212 | M212 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
K502 | R502 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K509 | N509 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
T537 | P537 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
T537 | M537 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K632 | N632 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |