iPTMnet Report for O95926 (SYF2)
Protein Information
UniProt AC / UniProt ID | O95926 / SYF2_HUMAN |
Protein Name | Pre-mRNA-splicing factor SYF2 |
Gene Name | Name: SYF2 Synonyms:CBPIN,GCIPIP; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O95926 |
PRO Name | pre-mRNA-splicing factor SYF2 (human) |
Definition | A pre-mRNA-splicing factor SYF2 that is encoded in the genome of human. |
Short Label | hSYF2 |
Category | organism-gene |
O95926 (SYF2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 22814378 | ||
S13 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y95 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y127 | Phosphorylation | score1 | PhosphoSitePlus | |||
K143 | Sumoylation | score1 | PhosphoSitePlus | |||
Y149 | Phosphorylation | score1 | PhosphoSitePlus | |||
K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y196 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y210 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y226 | Phosphorylation | score1 | PhosphoSitePlus | |||
K228 | Acetylation | score1 | PhosphoSitePlus | |||
Y229 | Phosphorylation | score1 | PhosphoSitePlus | |||
K234 | Sumoylation | score1 | PhosphoSitePlus | |||
K234 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y196 | * | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
K228 | E228 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K234 | R234 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |