iPTMnet Report for O95926 (SYF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95926 / SYF2_HUMAN
Protein Name Pre-mRNA-splicing factor SYF2
Gene Name Name: SYF2
Synonyms:CBPIN,GCIPIP;
Organism Homo sapiens (Human)

PRO ID PR:O95926
DAG View
PRO Name pre-mRNA-splicing factor SYF2 (human)
Definition A pre-mRNA-splicing factor SYF2 that is encoded in the genome of human.
Short Label hSYF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95926 (SYF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
S13 Phosphorylation PhosphoSitePlus
Y95 Phosphorylation PhosphoSitePlus
Y127 Phosphorylation PhosphoSitePlus
K143 Sumoylation PhosphoSitePlus
Y149 Phosphorylation PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
Y196 Phosphorylation PhosphoSitePlus
Y210 Phosphorylation PhosphoSitePlus
Y226 Phosphorylation PhosphoSitePlus
K228 Acetylation PhosphoSitePlus
Y229 Phosphorylation PhosphoSitePlus
K234 Sumoylation PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y196 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K228 E228 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K234 R234 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]