iPTMnet Report for O95863 (SNAI1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95863 / SNAI1_HUMAN
Protein Name Zinc finger protein SNAI1
Gene Name Name: SNAI1
Synonyms:SNAH;
Organism Homo sapiens (Human)

PRO ID PR:O95863
DAG View
PRO Name zinc finger protein SNAI1 (human)
Definition A zinc finger protein SNAI1 that is encoded in the genome of human.
Short Label hSNAI1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95863 (SNAI1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation P17612 (PRKACA) , P68400 (CSNK2A1) , Q15139 (PRKD1) neXtProt   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 22276203, 22791710, 19923321, ...25203322, 20940406
S82 Phosphorylation P28482 (MAPK1) PhosphoSitePlus   RLIMS-P   UniProt 19923321, 23644467
S90 Phosphorylation PhosphoSitePlus
S92 Phosphorylation P68400 (CSNK2A1) , P49841 (GSK3B) , P67870 (CSNK2B) , Q13131 (PRKAA1) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 19923321, 15448698, 15302935, ...22562247
S96 Phosphorylation P49841 (GSK3B) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 29618518, 15647282, 26246285, ...19004823, 20305697, 15448698
K98 Ubiquitination PhosphoSitePlus
S100 Phosphorylation P49841 (GSK3B) , Q13315 (ATM) PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 29618518, 19004823, 20305697, ...22923499, 15448698, 23891091, 23449453
S104 Phosphorylation P49841 (GSK3B) , P49674 (CSNK1E) , P28482 (MAPK1) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15647282, 19923321, 23644467, ...20305697, 15448698, 23449453
S107 Phosphorylation P49674 (CSNK1E) , P49841 (GSK3B) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15647282, 19923321, 19004823, ...20305697, 15448698, 23449453
S111 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor   UniProt 19004823, 20305697, 15448698
S112 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 20959806
S115 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor   UniProt 19004823, 20305697, 15448698
S119 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor   UniProt 19004823, 20305697, 15448698
K137 Ubiquitination PhosphoSitePlus
K146 Acetylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K187 Acetylation PhosphoSitePlus
T201 Phosphorylation PhosphoSitePlus
T203 Phosphorylation Q9NRM7 (LATS2) IntAct   neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 24157836, 34335956, 30800215, ...21952048
K206 Ubiquitination PhosphoSitePlus
K234 Sumoylation PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
S246 Phosphorylation Q13153 (PAK1) , Q16512 (PKN1) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 19860811, 25125660, 19923321, ...28423359, 15833848
S249 Phosphorylation PhosphoSitePlus   RLIMS-P 30804505


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O94782 (USP1) S331 O95863 (SNAI1) unknown eFIP 31086816
Phosphorylation O95863 (SNAI1) S11 P58215 (LOXL3) increased_association eFIP 31340433


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S112 F112 Biomuta [ cosmic ]
S115 F115 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S119 F119 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K187 E187 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K187 N187 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S246 F246 Biomuta DOID:4159 / skin cancer [ cosmic ]