Protein Information

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UniProt AC / UniProt ID O95863 / SNAI1_HUMAN
Protein Name Zinc finger protein SNAI1
Gene Name Name: SNAI1
Synonyms:SNAH;
Organism Homo sapiens (Human)

PRO ID PR:O95863
DAG View
PRO Name zinc finger protein SNAI1 (human)
Definition A zinc finger protein SNAI1 that is encoded in the genome of human.
Short Label hSNAI1
Category organism-gene

Interactive Sequence View

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O95863 (SNAI1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 22276203, 22791710, 19923321, ...25203322, 20940406
S11 Phosphorylation P17612 (PRKACA) PhosphoSitePlus 19923321
S11 Phosphorylation P68400 (CSNK2A1) Signor 19923321
S11 Phosphorylation Q15139 (PRKD1) neXtProt   PhosphoSitePlus   RLIMS-P+   Signor 25203322, 22276203, 20940406, ...22791710
S82 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 19923321, 23644467
S82 Phosphorylation P28482 (MAPK1) PhosphoSitePlus 23644467
S90 Phosphorylation PhosphoSitePlus
S92 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 19923321, 15448698, 15302935, ...22562247
S92 Phosphorylation P49841 (GSK3B) neXtProt 15448698
S92 Phosphorylation P67870 (CSNK2B) PhosphoSitePlus 22562247
S92 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 19923321, 22562247
S92 Phosphorylation Q13131 (PRKAA1) Signor 19923321
S96 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 29618518, 15647282, 26246285, ...19004823, 20305697, 15448698
S96 Phosphorylation P49841 (GSK3B) neXtProt   PhosphoSitePlus   Signor 19004823, 20305697, 15448698
K98 Ubiquitination PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 29618518, 19004823, 20305697, ...22923499, 15448698, 23891091, 23449453
S100 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 20305697, 19004823, 15448698
S100 Phosphorylation Q13315 (ATM) RLIMS-P+ 23891091
S104 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15647282, 19923321, 23644467, ...20305697, 15448698, 23449453
S104 Phosphorylation P28482 (MAPK1) PhosphoSitePlus 23644467
S104 Phosphorylation P49674 (CSNK1E) PhosphoSitePlus 20305697
S104 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 20305697, 15448698, 15647282
S107 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15647282, 19923321, 19004823, ...20305697, 15448698, 23449453
S107 Phosphorylation P49674 (CSNK1E) PhosphoSitePlus 20305697
S107 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 19004823, 20305697, 15448698, ...15647282
S111 Phosphorylation PhosphoSitePlus   Signor   UniProt 19004823, 20305697, 15448698
S111 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 19004823, 20305697, 15448698
S112 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 20959806
S115 Phosphorylation PhosphoSitePlus   Signor   UniProt 19004823, 20305697, 15448698
S115 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 19004823, 20305697, 15448698
S119 Phosphorylation PhosphoSitePlus   Signor   UniProt 19004823, 20305697, 15448698
S119 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 20305697, 19004823, 15448698
K137 Ubiquitination PhosphoSitePlus
K146 Acetylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K187 Acetylation PhosphoSitePlus
T201 Phosphorylation PhosphoSitePlus
T203 Phosphorylation IntAct   neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 24157836, 34335956, 30800215, ...21952048
T203 Phosphorylation Q9NRM7 (LATS2) neXtProt   PhosphoSitePlus   Signor 21952048
K206 Ubiquitination PhosphoSitePlus
K234 Sumoylation PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
S246 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 19860811, 25125660, 19923321, ...28423359, 15833848
S246 Phosphorylation Q13153 (PAK1) phospho.ELM   PhosphoSitePlus   Signor 15833848, 25125660
S246 Phosphorylation Q16512 (PKN1) Signor 15833848
S249 Phosphorylation PhosphoSitePlus   RLIMS-P 30804505


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O94782 (USP1) S331 O95863 (SNAI1) unknown eFIP 31086816
Phosphorylation O95863 (SNAI1) S11 P58215 (LOXL3) increased_association eFIP 31340433


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S112 F112 Biomuta [ cosmic ]
S115 F115 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S119 F119 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K187 E187 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K187 N187 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S246 F246 Biomuta DOID:4159 / skin cancer [ cosmic ]