iPTMnet Report for O95461 (LARGE1)
Protein Information
| UniProt AC / UniProt ID | O95461 / LARG1_HUMAN |
| Protein Name | Xylosyl- and glucuronyltransferase LARGE1 |
| Gene Name | Name: LARGE1 Synonyms:KIAA0609,LARGE; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O95461 |
| PRO Name | xylosyl- and glucuronyltransferase LARGE1 (human) |
| Definition | A xylosyl- and glucuronyltransferase LARGE1 that is encoded in the genome of human. |
| Short Label | hLARGE1 |
| Category | organism-gene |
DAG ViewO95461 (LARGE1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N122 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| Y295 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y558 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y570 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y573 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T588 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T599 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y602 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K728 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y295 | H295 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
| Y558 | C558 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
