iPTMnet Report for O95461 (LARGE1)
Protein Information
UniProt AC / UniProt ID | O95461 / LARG1_HUMAN |
Protein Name | Xylosyl- and glucuronyltransferase LARGE1 |
Gene Name | Name: LARGE1 Synonyms:KIAA0609,LARGE; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O95461 |
PRO Name | xylosyl- and glucuronyltransferase LARGE1 (human) |
Definition | A xylosyl- and glucuronyltransferase LARGE1 that is encoded in the genome of human. |
Short Label | hLARGE1 |
Category | organism-gene |
O95461 (LARGE1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N122 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
Y295 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y558 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y570 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y573 | Phosphorylation | score1 | PhosphoSitePlus | |||
T588 | Phosphorylation | score1 | PhosphoSitePlus | |||
T599 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y602 | Phosphorylation | score1 | PhosphoSitePlus | |||
K728 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y295 | H295 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
Y558 | C558 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |