iPTMnet Report for O95450 (ADAMTS2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95450 / ATS2_HUMAN
Protein Name A disintegrin and metalloproteinase with thrombospondin motifs 2 precursor
Gene Name Name: ADAMTS2
Synonyms:PCINP,PCPNI;
Organism Homo sapiens (Human)

PRO ID PR:O95450
DAG View
PRO Name a disintegrin and metalloproteinase with thrombospondin motifs 2 (human)
Definition An a disintegrin and metalloproteinase with thrombospondin motifs 2 that is encoded in the genome of human.
Short Label hADAMTS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95450 (ADAMTS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T64 O-Glycosylation PhosphoSitePlus
Y524 Phosphorylation PhosphoSitePlus
T537 Phosphorylation PhosphoSitePlus
Y658 Phosphorylation PhosphoSitePlus
S661 Phosphorylation PhosphoSitePlus
T664 Phosphorylation PhosphoSitePlus
S669 Phosphorylation PhosphoSitePlus
Y682 Phosphorylation PhosphoSitePlus
S720 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K530 Acetylation PhosphoSitePlus
K543 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y658 * Biomuta DOID:3571 / liver cancer [ icgc ]
S661 Y661 Biomuta DOID:3571 / liver cancer [ icgc ]
Y682 * Biomuta DOID:3571 / liver cancer [ icgc ]