Protein Information

Cytoscape View


UniProt AC / UniProt ID O95450 / ATS2_HUMAN
Protein Name A disintegrin and metalloproteinase with thrombospondin motifs 2 precursor
Gene Name Name: ADAMTS2
Synonyms:PCINP,PCPNI;
Organism Homo sapiens (Human)

PRO ID PR:O95450
DAG View
PRO Name a disintegrin and metalloproteinase with thrombospondin motifs 2 (human)
Definition An a disintegrin and metalloproteinase with thrombospondin motifs 2 that is encoded in the genome of human.
Short Label hADAMTS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95450 (ADAMTS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T64 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
Y524 Phosphorylation PhosphoSitePlus
T537 Phosphorylation PhosphoSitePlus
Y658 Phosphorylation PhosphoSitePlus
S661 Phosphorylation PhosphoSitePlus
T664 Phosphorylation PhosphoSitePlus
S669 Phosphorylation PhosphoSitePlus
Y682 Phosphorylation PhosphoSitePlus
S720 Phosphorylation PhosphoSitePlus
T1127 O-Glycosylation GlyGen 30459171
Site PTM Type PTM Enzyme Score Source PMID
K530 Acetylation PhosphoSitePlus
K543 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K543 N543 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]