iPTMnet Report for O95450 (ADAMTS2)
Protein Information
UniProt AC / UniProt ID | O95450 / ATS2_HUMAN |
Protein Name | A disintegrin and metalloproteinase with thrombospondin motifs 2 precursor |
Gene Name | Name: ADAMTS2 Synonyms:PCINP,PCPNI; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O95450 |
PRO Name | a disintegrin and metalloproteinase with thrombospondin motifs 2 (human) |
Definition | An a disintegrin and metalloproteinase with thrombospondin motifs 2 that is encoded in the genome of human. |
Short Label | hADAMTS2 |
Category | organism-gene |
O95450 (ADAMTS2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T64 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
Y524 | Phosphorylation | score1 | PhosphoSitePlus | |||
T537 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y658 | Phosphorylation | score1 | PhosphoSitePlus | |||
S661 | Phosphorylation | score1 | PhosphoSitePlus | |||
T664 | Phosphorylation | score1 | PhosphoSitePlus | |||
S669 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y682 | Phosphorylation | score1 | PhosphoSitePlus | |||
S720 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1127 | O-Glycosylation | score1 | GlyGen | 30459171 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K530 | Acetylation | score1 | PhosphoSitePlus | |||
K543 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K543 | N543 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |