Protein Information

Cytoscape View


UniProt AC / UniProt ID O95278 / EPM2A_HUMAN
Protein Name Laforin
Gene Name Name: EPM2A
Organism Homo sapiens (Human)

PRO ID PR:O95278
DAG View
PRO Name laforin isoforms 1/2/4/5/6/7/8 (human)
Definition A laforin (human), isoforms 1, 2, 4, 5, 6, 7, and 8.
Short Label hEPM2A/iso:[1/2/4/5/6/7/8]
Category organism-seqgroup

Interactive Sequence View

Select/align proteoforms across species


O95278 (EPM2A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Ubiquitination PRO
S25 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 21728993
S25 Phosphorylation Q13131 (PRKAA1) PhosphoSitePlus 21728993
Y304 Phosphorylation PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
R325 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S147 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R325 C325 Biomuta DOID:1909 / melanoma [ tcga ]