iPTMnet Report for O95208 (EPN2)
Protein Information
UniProt AC / UniProt ID | O95208 / EPN2_HUMAN |
Protein Name | Epsin-2 |
Gene Name | Name: EPN2 Synonyms:KIAA1065; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O95208 |
PRO Name | epsin-2 (human) |
Definition | An epsin-2 that is encoded in the genome of human. |
Short Label | hEPN2 |
Category | organism-gene |
O95208 (EPN2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T2 | Phosphorylation | score1 | PhosphoSitePlus | |||
S4 | Phosphorylation | score1 | PhosphoSitePlus | |||
S5 | Phosphorylation | score1 | PhosphoSitePlus | |||
K11 | Ubiquitination | score1 | PhosphoSitePlus | |||
K69 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y83 | Phosphorylation | score1 | PhosphoSitePlus | |||
K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
K117 | Ubiquitination | score1 | PhosphoSitePlus | |||
K128 | Ubiquitination | score1 | PhosphoSitePlus | |||
K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
K141 | Ubiquitination | score1 | PhosphoSitePlus | |||
T150 | Phosphorylation | score1 | PhosphoSitePlus | |||
R153 | Phosphorylation | score1 | UniProt | 21406692, 17081983, 24275569 | ||
Q156 | Phosphorylation | score1 | UniProt | 21406692 | ||
S163 | Phosphorylation | score1 | PhosphoSitePlus | |||
R170 | Methylation | score1 | PhosphoSitePlus | |||
S172 | Phosphorylation | score1 | PhosphoSitePlus | |||
S173 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S178 | Phosphorylation | score1 | PhosphoSitePlus | |||
S180 | Phosphorylation | score1 | PhosphoSitePlus | |||
S182 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y186 | Phosphorylation | score1 | PhosphoSitePlus | |||
S192 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 17081983, 24275569 | ||
S195 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
S199 | Phosphorylation | score1 | PhosphoSitePlus | |||
S237 | Phosphorylation | score1 | PhosphoSitePlus | |||
T249 | Phosphorylation | score1 | PhosphoSitePlus | |||
T272 | Phosphorylation | score1 | PhosphoSitePlus | |||
S273 | Phosphorylation | score1 | PhosphoSitePlus | |||
S287 | Phosphorylation | score1 | PhosphoSitePlus | |||
T316 | Phosphorylation | score1 | PhosphoSitePlus | |||
K318 | Ubiquitination | score1 | PhosphoSitePlus | |||
S327 | Phosphorylation | score1 | PhosphoSitePlus | |||
S408 | Phosphorylation | score1 | PhosphoSitePlus | |||
S420 | Phosphorylation | score1 | PhosphoSitePlus | |||
K423 | Acetylation | score1 | PhosphoSitePlus | |||
K423 | Methylation | score1 | PhosphoSitePlus | |||
K423 | Ubiquitination | score1 | PhosphoSitePlus | |||
S426 | Phosphorylation | score1 | PhosphoSitePlus | |||
S486 | Phosphorylation | score1 | PhosphoSitePlus | |||
S492 | Phosphorylation | score1 | PhosphoSitePlus | |||
S504 | Phosphorylation | score1 | PhosphoSitePlus | |||
T508 | Phosphorylation | score1 | PhosphoSitePlus | |||
S511 | Phosphorylation | score1 | PhosphoSitePlus | |||
S570 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S578 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S622 | Phosphorylation | score1 | PhosphoSitePlus | |||
S628 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y83 | Phosphorylation | score0 | HPRD | 20068231 | ||
S172 | Phosphorylation | score0 | HPRD | 18452278 | ||
S173 | Phosphorylation | score0 | HPRD | 15345747 | ||
S182 | Phosphorylation | score0 | HPRD | 15345747 | ||
S492 | Phosphorylation | score0 | HPRD | 19413330 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y83 | Phosphorylation | score0 | HPRD | 20068231 | ||
S172 | Phosphorylation | score0 | HPRD | 18452278 | ||
S173 | Phosphorylation | score0 | HPRD | 15345747 | ||
S182 | Phosphorylation | score0 | HPRD | 15345747 | ||
Y186 | Phosphorylation | score1 | PhosphoSitePlus | |||
K188 | Ubiquitination | score1 | PhosphoSitePlus | |||
S192 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19651622, 17081983, 20068231, ... | ||
S195 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19651622, 17081983, 20068231 | ||
Y196 | Phosphorylation | score1 | PhosphoSitePlus | |||
S199 | Phosphorylation | score1 | PhosphoSitePlus | |||
T200 | Phosphorylation | score1 | PhosphoSitePlus | |||
S201 | Phosphorylation | score1 | PhosphoSitePlus | |||
T259 | Phosphorylation | score1 | PhosphoSitePlus | |||
S435 | Phosphorylation | score0 | HPRD | 19413330 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S4 | L4 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
K69 | T69 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
K107 | N107 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
R153 | L153 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S182 | P182 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
Y186 | N186 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
S199 | L199 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S201 | T201 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
T259 | R259 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T316 | R316 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S327 | C327 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S408 | L408 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
K423 | N423 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |