iPTMnet Report for O94887 (FARP2)
Protein Information
UniProt AC / UniProt ID | O94887 / FARP2_HUMAN |
Protein Name | FERM, ARHGEF and pleckstrin domain-containing protein 2 |
Gene Name | Name: FARP2 Synonyms:KIAA0793,PLEKHC3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O94887 |
PRO Name | FERM, ARHGEF and pleckstrin domain-containing protein 2 (human) |
Definition | A FERM, ARHGEF and pleckstrin domain-containing protein 2 that is encoded in the genome of human. |
Short Label | hFARP2 |
Category | organism-gene |
O94887 (FARP2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y8 | Phosphorylation | score1 | PhosphoSitePlus | |||
T22 | Phosphorylation | score1 | PhosphoSitePlus | |||
S27 | Phosphorylation | score1 | PhosphoSitePlus | |||
T28 | Phosphorylation | score1 | PhosphoSitePlus | |||
T34 | Phosphorylation | score1 | PhosphoSitePlus | |||
K49 | Ubiquitination | score1 | PhosphoSitePlus | |||
C82 | Methylation | score1 | IEDB | 31844290 | ||
K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
K199 | Ubiquitination | score1 | PhosphoSitePlus | |||
K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
K331 | Ubiquitination | score1 | PhosphoSitePlus | |||
S336 | Phosphorylation | score1 | PhosphoSitePlus | |||
R337 | Methylation | score1 | PhosphoSitePlus | |||
S340 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 30872454 | ||
R342 | Methylation | score1 | PhosphoSitePlus | |||
S344 | Phosphorylation | score1 | PhosphoSitePlus | |||
K349 | Ubiquitination | score1 | PhosphoSitePlus | |||
K356 | Ubiquitination | score1 | PhosphoSitePlus | |||
S358 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y365 | Phosphorylation | score1 | PhosphoSitePlus | |||
S370 | Phosphorylation | score0 | RLIMS-P | 30872454 | ||
T380 | Phosphorylation | score1 | PhosphoSitePlus | |||
K385 | Ubiquitination | score1 | PhosphoSitePlus | |||
S387 | Phosphorylation | score1 | PhosphoSitePlus | |||
S389 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T396 | Phosphorylation | score1 | PhosphoSitePlus | |||
S399 | Phosphorylation | score1 | PhosphoSitePlus | |||
S401 | Phosphorylation | score1 | PhosphoSitePlus | |||
S402 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y407 | Phosphorylation | score1 | PhosphoSitePlus | |||
S410 | Phosphorylation | score1 | PhosphoSitePlus | |||
T413 | Phosphorylation | score1 | PhosphoSitePlus | |||
S417 | Phosphorylation | score1 | PhosphoSitePlus | |||
S425 | Phosphorylation | score1 | PhosphoSitePlus | |||
S428 | Phosphorylation | score1 | PhosphoSitePlus | |||
T430 | Phosphorylation | score1 | PhosphoSitePlus | |||
S435 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y436 | Phosphorylation | score1 | PhosphoSitePlus | |||
K438 | Ubiquitination | score1 | PhosphoSitePlus | |||
S439 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S446 | Phosphorylation | score1 | PhosphoSitePlus | |||
S473 | Phosphorylation | score1 | PhosphoSitePlus | |||
T474 | Phosphorylation | score1 | PhosphoSitePlus | |||
S476 | Phosphorylation | score1 | PhosphoSitePlus | |||
S480 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y537 | Phosphorylation | score1 | PhosphoSitePlus | |||
T574 | Phosphorylation | score1 | PhosphoSitePlus | |||
T577 | Phosphorylation | score1 | PhosphoSitePlus | |||
S581 | Phosphorylation | score1 | PhosphoSitePlus | |||
T645 | Phosphorylation | score1 | PhosphoSitePlus | |||
C820 | Methylation | score1 | IEDB | 31844290 | ||
T868 | Phosphorylation | score1 | PhosphoSitePlus | |||
S876 | Phosphorylation | score1 | PhosphoSitePlus | |||
S886 | Phosphorylation | score1 | PhosphoSitePlus | |||
T907 | Phosphorylation | score1 | PhosphoSitePlus | |||
T908 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y914 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1033 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S27 | N27 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
T34 | N34 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
R337 | W337 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S370 | N370 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S428 | F428 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S439 | G439 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S473 | F473 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T474 | M474 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S480 | F480 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T577 | M577 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S876 | F876 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] | |
S886 | L886 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |