Protein Information

Cytoscape View


UniProt AC / UniProt ID O94887 / FARP2_HUMAN
Protein Name FERM, ARHGEF and pleckstrin domain-containing protein 2
Gene Name Name: FARP2
Synonyms:KIAA0793,PLEKHC3;
Organism Homo sapiens (Human)

PRO ID PR:O94887
DAG View
PRO Name FERM, ARHGEF and pleckstrin domain-containing protein 2 (human)
Definition A FERM, ARHGEF and pleckstrin domain-containing protein 2 that is encoded in the genome of human.
Short Label hFARP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94887 (FARP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y8 Phosphorylation PhosphoSitePlus
T22 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
T28 Phosphorylation PhosphoSitePlus
T34 Phosphorylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
R337 Methylation PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
R342 Methylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus
Y365 Phosphorylation PhosphoSitePlus
T380 Phosphorylation PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
S389 Phosphorylation PhosphoSitePlus   UniProt 23186163
T396 Phosphorylation PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus
Y407 Phosphorylation PhosphoSitePlus
S410 Phosphorylation PhosphoSitePlus
T413 Phosphorylation PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus
T430 Phosphorylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
Y436 Phosphorylation PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
S439 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S446 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus
T474 Phosphorylation PhosphoSitePlus
S476 Phosphorylation PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
Y537 Phosphorylation PhosphoSitePlus
T574 Phosphorylation PhosphoSitePlus
T577 Phosphorylation PhosphoSitePlus
S581 Phosphorylation PhosphoSitePlus
T645 Phosphorylation PhosphoSitePlus
T868 Phosphorylation PhosphoSitePlus
S876 Phosphorylation PhosphoSitePlus
S886 Phosphorylation PhosphoSitePlus
T907 Phosphorylation PhosphoSitePlus
T908 Phosphorylation PhosphoSitePlus
Y914 Phosphorylation PhosphoSitePlus
S1033 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S428 Phosphorylation HPRD 19413330
T430 Phosphorylation HPRD 19413330
S439 Phosphorylation HPRD 18669648
S886 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T34 N34 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S336 I336 Biomuta DOID:3571 / liver cancer [ icgc ]
S428 F428 Biomuta DOID:1909 / melanoma [ tcga ]
S439 G439 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S876 F876 Biomuta DOID:3070 / malignant glioma [ cosmic ]