iPTMnet Report for O94887 (FARP2)
Protein Information
| UniProt AC / UniProt ID | O94887 / FARP2_HUMAN |
| Protein Name | FERM, ARHGEF and pleckstrin domain-containing protein 2 |
| Gene Name | Name: FARP2 Synonyms:KIAA0793,PLEKHC3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O94887 |
| PRO Name | FERM, ARHGEF and pleckstrin domain-containing protein 2 (human) |
| Definition | A FERM, ARHGEF and pleckstrin domain-containing protein 2 that is encoded in the genome of human. |
| Short Label | hFARP2 |
| Category | organism-gene |
O94887 (FARP2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y8 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T22 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S27 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T28 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T34 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K49 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C82 | Methylation | score1 | IEDB | 31844290 | ||
| K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K199 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K331 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S336 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R337 | Methylation | score1 | PhosphoSitePlus | |||
| S340 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 30872454 | ||
| R342 | Methylation | score1 | PhosphoSitePlus | |||
| S344 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K349 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K356 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S358 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y365 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S370 | Phosphorylation | score0 | RLIMS-P | 30872454 | ||
| T380 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K385 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S387 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S389 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T396 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S399 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S401 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S402 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y407 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S410 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T413 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S417 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S425 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S428 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T430 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S435 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y436 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K438 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S439 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| S446 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S473 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T474 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S476 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S480 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y537 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T574 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T577 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S581 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T645 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C820 | Methylation | score1 | IEDB | 31844290 | ||
| T868 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S876 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S886 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T907 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T908 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y914 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1033 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S27 | N27 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| T34 | N34 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| R337 | W337 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S370 | N370 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S428 | F428 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S439 | G439 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S473 | F473 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T474 | M474 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S480 | F480 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T577 | M577 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S876 | F876 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] | |
| S886 | L886 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |
DAG View