iPTMnet Report for O94769 (ECM2)
Protein Information
| UniProt AC / UniProt ID | O94769 / ECM2_HUMAN |
| Protein Name | Extracellular matrix protein 2 precursor |
| Gene Name | Name: ECM2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O94769 |
| PRO Name | extracellular matrix protein 2 (human) |
| Definition | An extracellular matrix protein 2 that is encoded in the genome of human. |
| Short Label | hECM2 |
| Category | organism-gene |
O94769 (ECM2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T58 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| Y74 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S84 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S213 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S241 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S245 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S304 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N377 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N378 | N-Glycosylation | score1 | GlyGen | 29741879, 24190977 | ||
| S382 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y544 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S622 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y74 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S84 | L84 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S213 | F213 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S304 | P304 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S382 | L382 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
| S622 | C622 | Biomuta | DOID:4362 / cervical cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ] |
DAG View