Protein Information

Cytoscape View


UniProt AC / UniProt ID O94769 / ECM2_HUMAN
Protein Name Extracellular matrix protein 2 precursor
Gene Name Name: ECM2
Organism Homo sapiens (Human)

PRO ID PR:O94769
DAG View
PRO Name extracellular matrix protein 2 (human)
Definition An extracellular matrix protein 2 that is encoded in the genome of human.
Short Label hECM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94769 (ECM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T58 O-Glycosylation GlyGen 30459171
Y74 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
S84 O-Glycosylation GlyGen 30459171
S213 Phosphorylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
N377 N-Glycosylation GlyGen 24190977
N378 N-Glycosylation GlyGen 29741879, 24190977
S382 Phosphorylation PhosphoSitePlus
Y544 Phosphorylation PhosphoSitePlus
S622 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S213 Phosphorylation HPRD 18702456, 20187088


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y74 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S84 L84 Biomuta DOID:4159 / skin cancer [ cosmic ]
S213 F213 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S304 P304 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S382 L382 Biomuta DOID:1319 / brain cancer [ icgc ]
S622 C622 Biomuta DOID:4362 / cervical cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]