iPTMnet Report for O76031 (CLPX)
Protein Information
UniProt AC / UniProt ID | O76031 / CLPX_HUMAN |
Protein Name | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial precursor |
Gene Name | Name: CLPX |
Organism | Homo sapiens (Human) |
PRO ID | PR:O76031 |
PRO Name | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial (human) |
Definition | An ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial that is encoded in the genome of human. |
Short Label | hCLPX |
Category | organism-gene |
O76031 (CLPX) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S29 | Phosphorylation | score1 | PhosphoSitePlus | |||
S36 | Phosphorylation | score1 | PhosphoSitePlus | |||
S66 | Phosphorylation | score1 | PhosphoSitePlus | |||
S71 | Phosphorylation | score1 | PhosphoSitePlus | |||
K90 | Ubiquitination | score1 | PhosphoSitePlus | |||
K98 | Acetylation | score1 | PhosphoSitePlus | |||
S152 | O-Glycosylation | score1 | GlyGen | 30379171, 28510447, 33465208 | ||
K178 | Acetylation | score1 | PhosphoSitePlus | |||
K187 | Methylation | score1 | PhosphoSitePlus | |||
K217 | Ubiquitination | score1 | PhosphoSitePlus | |||
S220 | Phosphorylation | score1 | PhosphoSitePlus | |||
T222 | Phosphorylation | score1 | PhosphoSitePlus | |||
K239 | Ubiquitination | score1 | PhosphoSitePlus | |||
R270 | Methylation | score1 | PhosphoSitePlus | |||
S277 | Phosphorylation | score1 | PhosphoSitePlus | |||
S278 | Phosphorylation | score1 | PhosphoSitePlus | |||
K286 | Ubiquitination | score1 | PhosphoSitePlus | |||
S297 | Phosphorylation | score1 | PhosphoSitePlus | |||
K299 | Ubiquitination | score1 | PhosphoSitePlus | |||
T300 | Phosphorylation | score1 | PhosphoSitePlus | |||
K349 | Ubiquitination | score1 | PhosphoSitePlus | |||
K362 | Ubiquitination | score1 | PhosphoSitePlus | |||
R373 | Methylation | score1 | PhosphoSitePlus | |||
T407 | Phosphorylation | score1 | PhosphoSitePlus | |||
T412 | Phosphorylation | score1 | PhosphoSitePlus | |||
T413 | Phosphorylation | score1 | PhosphoSitePlus | |||
S420 | Phosphorylation | score1 | PhosphoSitePlus | |||
K437 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K437 | Ubiquitination | score1 | PhosphoSitePlus | |||
T443 | Phosphorylation | score1 | PhosphoSitePlus | |||
K449 | Ubiquitination | score1 | PhosphoSitePlus | |||
S463 | O-Glycosylation | score1 | GlyGen | 30379171, 28510447, 33465208 | ||
K475 | Acetylation | score1 | PhosphoSitePlus | |||
Y529 | Phosphorylation | score1 | PhosphoSitePlus | |||
K548 | Ubiquitination | score1 | PhosphoSitePlus | |||
K591 | Acetylation | score1 | PhosphoSitePlus | |||
K597 | Acetylation | score1 | PhosphoSitePlus | |||
T607 | Phosphorylation | score1 | PhosphoSitePlus | |||
S610 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18452278 | ||
S611 | Phosphorylation | score1 | PhosphoSitePlus | |||
S617 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 23186163, 19690332, 18452278 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S29 | F29 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S36 | P36 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
K98 | E98 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
S220 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K349 | T349 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K362 | R362 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S420 | C420 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S611 | F611 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S617 | F617 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |