iPTMnet Report for O75912 (DGKI)
Protein Information
UniProt AC / UniProt ID | O75912 / DGKI_HUMAN |
Protein Name | Diacylglycerol kinase iota |
Gene Name | Name: DGKI |
Organism | Homo sapiens (Human) |
PRO ID | PR:O75912 |
PRO Name | diacylglycerol kinase iota (human) |
Definition | A diacylglycerol kinase iota that is encoded in the genome of human. |
Short Label | hDGKI |
Category | organism-gene |
O75912 (DGKI) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K296 | Acetylation | score1 | PhosphoSitePlus | |||
K367 | Acetylation | score1 | PhosphoSitePlus | |||
K553 | Ubiquitination | score1 | PhosphoSitePlus | |||
T591 | Phosphorylation | score1 | PhosphoSitePlus | |||
T594 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y788 | Phosphorylation | score1 | PhosphoSitePlus | |||
S820 | Phosphorylation | score1 | PhosphoSitePlus | |||
S825 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1049 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1053 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K367 | Q367 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K553 | I553 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S825 | C825 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S1049 | G1049 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |