Protein Information

Cytoscape View


UniProt AC / UniProt ID O75912 / DGKI_HUMAN
Protein Name Diacylglycerol kinase iota
Gene Name Name: DGKI
Organism Homo sapiens (Human)

PRO ID PR:O75912
DAG View
PRO Name diacylglycerol kinase iota (human)
Definition A diacylglycerol kinase iota that is encoded in the genome of human.
Short Label hDGKI
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75912 (DGKI) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K296 Acetylation PhosphoSitePlus
K367 Acetylation PhosphoSitePlus
K553 Ubiquitination PhosphoSitePlus
T591 Phosphorylation PhosphoSitePlus
T594 Phosphorylation PhosphoSitePlus
Y788 Phosphorylation PhosphoSitePlus
S820 Phosphorylation PhosphoSitePlus
S825 Phosphorylation PhosphoSitePlus
S1049 Phosphorylation PhosphoSitePlus
Y1053 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K367 Q367 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K553 I553 Biomuta DOID:1909 / melanoma [ tcga ]
S825 C825 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S1049 G1049 Biomuta DOID:1612 / breast cancer [ tcga ]