iPTMnet Report for O75912 (DGKI)
Protein Information
| UniProt AC / UniProt ID | O75912 / DGKI_HUMAN |
| Protein Name | Diacylglycerol kinase iota |
| Gene Name | Name: DGKI |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O75912 |
| PRO Name | diacylglycerol kinase iota (human) |
| Definition | A diacylglycerol kinase iota that is encoded in the genome of human. |
| Short Label | hDGKI |
| Category | organism-gene |
O75912 (DGKI) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K296 | Acetylation | score1 | PhosphoSitePlus | |||
| K367 | Acetylation | score1 | PhosphoSitePlus | |||
| K553 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T591 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T594 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y788 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S820 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S825 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1049 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1053 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K367 | Q367 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K553 | I553 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S825 | C825 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S1049 | G1049 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
DAG View