iPTMnet Report for O75881 (CYP7B1)
Protein Information
| UniProt AC / UniProt ID | O75881 / CP7B1_HUMAN |
| Protein Name | Cytochrome P450 7B1 |
| Gene Name | Name: CYP7B1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O75881 |
| PRO Name | cytochrome P450 7B1 (human) |
| Definition | A cytochrome P450 7B1 that is encoded in the genome of human. |
| Short Label | hCYP7B1 |
| Category | organism-gene |
DAG ViewO75881 (CYP7B1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T40 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T80 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K218 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K256 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S266 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T342 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S355 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S366 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T367 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S380 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y385 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K218 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K256 | N256 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S355 | I355 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S380 | L380 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] |
