Protein Information

Cytoscape View


UniProt AC / UniProt ID O75881 / CP7B1_HUMAN
Protein Name Cytochrome P450 7B1
Gene Name Name: CYP7B1
Organism Homo sapiens (Human)

PRO ID PR:O75881
DAG View
PRO Name cytochrome P450 7B1 (human)
Definition A cytochrome P450 7B1 that is encoded in the genome of human.
Short Label hCYP7B1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75881 (CYP7B1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T40 Phosphorylation PhosphoSitePlus
T80 Phosphorylation PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus
T342 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
T367 Phosphorylation PhosphoSitePlus
S380 Phosphorylation PhosphoSitePlus
Y385 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K218 * Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K256 N256 Biomuta DOID:363 / uterine cancer [ tcga ]
S266 R266 Biomuta DOID:3571 / liver cancer [ icgc ]
S366 * Biomuta DOID:11934 / head and neck cancer [ tcga ]
S380 L380 Biomuta DOID:5041 / esophageal cancer [ icgc ]