iPTMnet Report for O75689 (ADAP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75689 / ADAP1_HUMAN
Protein Name Arf-GAP with dual PH domain-containing protein 1
Gene Name Name: ADAP1
Synonyms:CENTA1;
Organism Homo sapiens (Human)

PRO ID PR:O75689
DAG View
PRO Name Arf-GAP with dual PH domain-containing protein 1 (human)
Definition An Arf-GAP with dual PH domain-containing protein 1 that is encoded in the genome of human.
Short Label hADAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75689 (ADAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S87 Phosphorylation Q02156 (PRKCE) , P17252 (PRKCA) PhosphoSitePlus   UniProt 12893243
K123 Ubiquitination PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
Y232 Phosphorylation PhosphoSitePlus
K272 Acetylation PhosphoSitePlus   UniProt 19608861
T276 Phosphorylation Q02156 (PRKCE) , P17252 (PRKCA) PhosphoSitePlus   UniProt 12893243
Y284 Phosphorylation PhosphoSitePlus
Y364 Phosphorylation PhosphoSitePlus   RLIMS-P 29659066
Site PTM Type PTM Enzyme Score Source PMID
S87 Phosphorylation P17252 (PRKCA) , Q02156 (PRKCE) HPRD 12893243
T276 Phosphorylation P17252 (PRKCA) , Q02156 (PRKCE) HPRD 12893243


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K216 E216 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y284 D284 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y364 H364 Biomuta DOID:1319 / brain cancer [ cosmic ]