iPTMnet Report for O75689 (ADAP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75689 / ADAP1_HUMAN
Protein Name Arf-GAP with dual PH domain-containing protein 1
Gene Name Name: ADAP1
Synonyms:CENTA1;
Organism Homo sapiens (Human)

PRO ID PR:O75689
DAG View
PRO Name Arf-GAP with dual PH domain-containing protein 1 (human)
Definition An Arf-GAP with dual PH domain-containing protein 1 that is encoded in the genome of human.
Short Label hADAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75689 (ADAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S87 Phosphorylation PhosphoSitePlus   UniProt 12893243
S87 Phosphorylation P17252 (PRKCA) PhosphoSitePlus 12893243
S87 Phosphorylation Q02156 (PRKCE) PhosphoSitePlus 12893243
K123 Ubiquitination PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
Y232 Phosphorylation PhosphoSitePlus
K272 Acetylation PhosphoSitePlus   UniProt 19608861
T276 Phosphorylation PhosphoSitePlus   UniProt 12893243
T276 Phosphorylation P17252 (PRKCA) PhosphoSitePlus 12893243
T276 Phosphorylation Q02156 (PRKCE) PhosphoSitePlus 12893243
Y284 Phosphorylation PhosphoSitePlus
Y364 Phosphorylation PhosphoSitePlus   RLIMS-P 29659066
Site PTM Type PTM Enzyme Score Source PMID
S87 Phosphorylation HPRD 12893243
S87 Phosphorylation P17252 (PRKCA) HPRD 12893243
S87 Phosphorylation Q02156 (PRKCE) HPRD 12893243
T276 Phosphorylation HPRD 12893243
T276 Phosphorylation P17252 (PRKCA) HPRD 12893243
T276 Phosphorylation Q02156 (PRKCE) HPRD 12893243


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K216 E216 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y284 D284 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y364 H364 Biomuta DOID:1319 / brain cancer [ cosmic ]