iPTMnet Report for O75648 (TRMU)
Protein Information
| UniProt AC / UniProt ID | O75648 / MTU1_HUMAN |
| Protein Name | Mitochondrial tRNA-specific 2-thiouridylase 1 |
| Gene Name | Name: TRMU Synonyms:MTU1,TRMT1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O75648 |
| PRO Name | mitochondrial tRNA-specific 2-thiouridylase 1 (human) |
| Definition | A mitochondrial tRNA-specific 2-thiouridylase 1 that is encoded in the genome of human. |
| Short Label | hTRMU |
| Category | organism-gene |
O75648 (TRMU) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T94 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K142 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C222 | Methylation | score1 | IEDB | 31844290 | ||
| K286 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R332 | Methylation | score1 | PhosphoSitePlus | |||
| Y391 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K395 | Ubiquitination | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S4 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R332 | P332 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |
DAG View