iPTMnet Report for O75531 (BANF1)
Protein Information
UniProt AC / UniProt ID | O75531 / BAF_HUMAN |
Protein Name | Barrier-to-autointegration factor |
Gene Name | Name: BANF1 Synonyms:BAF; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O75531 |
PRO Name | barrier-to-autointegration factor (human) |
Definition | A barrier-to-autointegration factor that is encoded in the genome of human. |
Short Label | hBANF1 |
Category | organism-gene |
O75531 (BANF1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score2 | PRO UniProt | 20068231 | ||
T2 | Acetylation | score1 | UniProt | 19413330 | ||
T2 | Phosphorylation | Q99986 (VRK1) , Q86Y07 (VRK2) | score4 | HPRD phospho.ELM PRO PhosphoSitePlus RLIMS-P Signor UniProt | 19413330, 24945635, 24265311, ... | |
T3 | Phosphorylation | Q86Y07 (VRK2) , Q99986 (VRK1) | score4 | HPRD phospho.ELM PRO PhosphoSitePlus RLIMS-P Signor UniProt | 19413330, 24945635, 24265311, ... | |
S4 | Phosphorylation | Q86Y07 (VRK2) , Q99986 (VRK1) , Q8IV63 (VRK3) | score4 | HPRD neXtProt phospho.ELM PRO PhosphoSitePlus RLIMS-P Signor UniProt | 19413330, 20511217, 31164634, ... | |
K6 | Acetylation | score1 | PhosphoSitePlus | |||
K6 | Sumoylation | score1 | PhosphoSitePlus | |||
K18 | Ubiquitination | score1 | PhosphoSitePlus | |||
S22 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
K32 | Ubiquitination | score1 | PhosphoSitePlus | |||
R37 | Methylation | score1 | PhosphoSitePlus | |||
Y43 | Phosphorylation | score1 | PhosphoSitePlus | |||
K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
R60 | Methylation | score1 | PhosphoSitePlus | |||
K64 | Acetylation | score1 | PhosphoSitePlus | |||
K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
R82 | Methylation | score1 | PhosphoSitePlus |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000036220 (hBANF1/Ac:1) | acM1 | PRO | |||
PR:000046460 (hBANF1/Phos:2) | pT2,pT3,pS4 | PRO |
PTM-dependent PPI
PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
---|---|---|---|---|---|---|---|
Phosphorylation | O75531 (BANF1) | S4 | P50402 (EMD) | unknown | eFIP | 16371512 | |
Phosphorylation | Q9Y2U8 (LEMD3) | S402 | O75531 (BANF1) | unknown | eFIP | 19166343 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S4 | F4 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
S22 | N22 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K32 | * | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
R60 | Q60 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
R82 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |