Protein Information

Cytoscape View


UniProt AC / UniProt ID O75339 / CILP1_HUMAN
Protein Name Cartilage intermediate layer protein 1 precursor
Gene Name Name: CILP
ORFNames:UNQ602/PRO1188;
Organism Homo sapiens (Human)

PRO ID PR:O75339
DAG View
PRO Name cartilage intermediate layer protein 1 (human)
Definition A cartilage intermediate layer protein 1 that is encoded in the genome of human.
Short Label hCILP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75339 (CILP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T27 Phosphorylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
T96 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T97 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T105 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
N129 N-Glycosylation GlyGen 23090970, 29741879, 24190977
N132 N-Glycosylation GlyGen 29741879
T288 Phosphorylation PhosphoSitePlus
T292 Phosphorylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
Y310 Phosphorylation PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus
N346 N-Glycosylation GlyGen   UniProt 29741879, 9722584
T348 Phosphorylation PhosphoSitePlus
K360 Ubiquitination PhosphoSitePlus
Y374 Phosphorylation PhosphoSitePlus
T400 Phosphorylation PhosphoSitePlus
N420 N-Glycosylation GlyGen 29741879, 24190977
N550 N-Glycosylation GlyGen 29741879
T551 Phosphorylation PhosphoSitePlus
T552 Phosphorylation PhosphoSitePlus
N631 N-Glycosylation GlyGen 29741879
K755 Methylation PhosphoSitePlus
T784 Phosphorylation PhosphoSitePlus
S1135 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
T1136 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
S1140 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
S1140 Phosphorylation PhosphoSitePlus
T1145 O-Glycosylation GlyGen   PhosphoSitePlus 23584533


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T105 N105 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
N346 Y346 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N550 T550 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
N631 S631 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S1140 Y1140 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]