iPTMnet Report for O75339 (CILP)
Protein Information
| UniProt AC / UniProt ID | O75339 / CILP1_HUMAN |
| Protein Name | Cartilage intermediate layer protein 1 precursor |
| Gene Name | Name: CILP ORFNames:UNQ602/PRO1188; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O75339 |
| PRO Name | cartilage intermediate layer protein 1 (human) |
| Definition | A cartilage intermediate layer protein 1 that is encoded in the genome of human. |
| Short Label | hCILP |
| Category | organism-gene |
O75339 (CILP) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T27 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S29 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T96 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T97 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T105 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| N129 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
| N132 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| T288 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T292 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S293 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T298 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y310 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y341 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N346 | N-Glycosylation | score4 | GlyGen UniProt | 29741879, 9722584 | ||
| T348 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K360 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y374 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T400 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N420 | N-Glycosylation | score1 | GlyGen | 29741879, 24190977 | ||
| N550 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| T551 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T552 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N631 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| K755 | Methylation | score1 | PhosphoSitePlus | |||
| T784 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1135 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171 | ||
| T1136 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171 | ||
| S1140 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171 | ||
| S1140 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1145 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T105 | N105 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| N346 | Y346 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| N550 | T550 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
| N631 | S631 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S1140 | Y1140 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View