iPTMnet Report for O60941 (DTNB)
Protein Information
| UniProt AC / UniProt ID | O60941 / DTNB_HUMAN |
| Protein Name | Dystrobrevin beta |
| Gene Name | Name: DTNB |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O60941 |
| PRO Name | dystrobrevin beta (human) |
| Definition | A dystrobrevin beta that is encoded in the genome of human. |
| Short Label | hDTNB |
| Category | organism-gene |
DAG ViewO60941 (DTNB) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 25732826 | ||
| K10 | Acetylation | score1 | PhosphoSitePlus | |||
| T11 | Phosphorylation | P17612 (PRKACA) | score4 | neXtProt PhosphoSitePlus | 17610895, 22978324 | |
| T69 | Phosphorylation | P17252 (PRKCA) | score2 | PhosphoSitePlus | 22978324 | |
| T128 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K143 | Acetylation | score1 | PhosphoSitePlus | |||
| T179 | Phosphorylation | P17252 (PRKCA) | score2 | PhosphoSitePlus | 22978324 | |
| T212 | Phosphorylation | P17252 (PRKCA) | score2 | PhosphoSitePlus | 22978324 | |
| S294 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S364 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S394 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S396 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T420 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T424 | Phosphorylation | P17612 (PRKACA) | score4 | neXtProt PhosphoSitePlus | 17610895, 22978324 | |
| S427 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T468 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T529 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S531 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T534 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S535 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T537 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S552 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S555 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T556 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S594 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S608 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K624 | Acetylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S552 | Phosphorylation | score0 | HPRD | 18669648 | ||
| T556 | Phosphorylation | score0 | HPRD | 18669648 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T358 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S364 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S366 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S550 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T128 | M128 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T212 | I212 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T468 | S468 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T468 | I468 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| S552 | P552 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S594 | C594 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| K624 | R624 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] |
