iPTMnet Report for O60941 (DTNB)
Protein Information
UniProt AC / UniProt ID | O60941 / DTNB_HUMAN |
Protein Name | Dystrobrevin beta |
Gene Name | Name: DTNB |
Organism | Homo sapiens (Human) |
PRO ID | PR:O60941 |
PRO Name | dystrobrevin beta (human) |
Definition | A dystrobrevin beta that is encoded in the genome of human. |
Short Label | hDTNB |
Category | organism-gene |
O60941 (DTNB) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 25732826 | ||
K10 | Acetylation | score1 | PhosphoSitePlus | |||
T11 | Phosphorylation | score4 | neXtProt PhosphoSitePlus | 17610895, 22978324 | ||
T11 | Phosphorylation | P17612 (PRKACA) | score4 | neXtProt PhosphoSitePlus | 17610895, 22978324 | |
T69 | Phosphorylation | score2 | PhosphoSitePlus | 22978324 | ||
T69 | Phosphorylation | P17252 (PRKCA) | score2 | PhosphoSitePlus | 22978324 | |
T128 | Phosphorylation | score1 | PhosphoSitePlus | |||
K143 | Acetylation | score1 | PhosphoSitePlus | |||
T179 | Phosphorylation | score2 | PhosphoSitePlus | 22978324 | ||
T179 | Phosphorylation | P17252 (PRKCA) | score2 | PhosphoSitePlus | 22978324 | |
T212 | Phosphorylation | score2 | PhosphoSitePlus | 22978324 | ||
T212 | Phosphorylation | P17252 (PRKCA) | score2 | PhosphoSitePlus | 22978324 | |
S294 | Phosphorylation | score1 | PhosphoSitePlus | |||
S364 | Phosphorylation | score1 | PhosphoSitePlus | |||
S394 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S396 | Phosphorylation | score1 | PhosphoSitePlus | |||
T420 | Phosphorylation | score1 | PhosphoSitePlus | |||
T424 | Phosphorylation | score4 | neXtProt PhosphoSitePlus | 17610895, 22978324 | ||
T424 | Phosphorylation | P17612 (PRKACA) | score4 | neXtProt PhosphoSitePlus | 17610895, 22978324 | |
S427 | Phosphorylation | score1 | PhosphoSitePlus | |||
T468 | Phosphorylation | score1 | PhosphoSitePlus | |||
T529 | Phosphorylation | score1 | PhosphoSitePlus | |||
S531 | Phosphorylation | score1 | PhosphoSitePlus | |||
T534 | Phosphorylation | score1 | PhosphoSitePlus | |||
S535 | Phosphorylation | score1 | PhosphoSitePlus | |||
T537 | Phosphorylation | score1 | PhosphoSitePlus | |||
S552 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S555 | Phosphorylation | score1 | PhosphoSitePlus | |||
T556 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S594 | Phosphorylation | score1 | PhosphoSitePlus | |||
S608 | Phosphorylation | score1 | PhosphoSitePlus | |||
K624 | Acetylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S552 | Phosphorylation | score0 | HPRD | 18669648 | ||
T556 | Phosphorylation | score0 | HPRD | 18669648 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T358 | Phosphorylation | score1 | PhosphoSitePlus | |||
S364 | Phosphorylation | score1 | PhosphoSitePlus | |||
S366 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S550 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T128 | M128 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T212 | I212 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T468 | S468 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T468 | I468 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
S552 | P552 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S594 | C594 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K624 | R624 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] |