Protein Information

Cytoscape View


UniProt AC / UniProt ID O60825 / F262_HUMAN
Protein Name 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
Gene Name Name: PFKFB2
Organism Homo sapiens (Human)

PRO ID PR:O60825
DAG View
PRO Name 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (human)
Definition A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 that is encoded in the genome of human.
Short Label hPFKFB2
Category organism-gene

Interactive Sequence View

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O60825 (PFKFB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 22814378
S13 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
Y356 Phosphorylation PhosphoSitePlus
Y358 Phosphorylation PhosphoSitePlus
Y366 Phosphorylation PhosphoSitePlus
T458 Phosphorylation PhosphoSitePlus
S466 Phosphorylation P23443 (RPS6KB1) , Q13131 (PRKAA1) , P31749 (AKT1) , P17612 (PRKACA) , P51812 (RPS6KA3) , A0A0A0N0L1 (AMPK alpha 2) , P54646 (PRKAA2) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 21406692, 11069105, 23186163, ...18220336, 10521487, 20958264, 18669648, 12853467, 2846551, 20068231, 9211863
T468 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18220336
S471 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S472 Phosphorylation PhosphoSitePlus
T475 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
Y482 Phosphorylation PhosphoSitePlus
S483 Phosphorylation P31749 (AKT1) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 23457334, 20958264, 18669648, ...12853467, 20068231
S486 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S493 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S29 Phosphorylation HPRD 20068231
S32 Phosphorylation HPRD 20068231
S466 Phosphorylation P31749 (AKT1) , Q13131 (PRKAA1) , P54646 (PRKAA2) , P17612 (PRKACA) HPRD 19413330, 18767875, 19651622, ...18669648, 12853467, 20068231, 17924679
T468 Phosphorylation HPRD 18767875, 18669648, 20068231
S471 Phosphorylation HPRD 18669648
T475 Phosphorylation P17252 (PRKCA) HPRD 18669648, 1322130
S483 Phosphorylation P31749 (AKT1) HPRD 12853467, 19651622, 18669648, ...20068231
S486 Phosphorylation HPRD 18669648
S493 Phosphorylation HPRD 19651622, 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S29 Phosphorylation HPRD 20068231
S32 Phosphorylation HPRD 20068231
S463 Phosphorylation PhosphoSitePlus