iPTMnet Report for O60240 (PLIN1)
Protein Information
| UniProt AC / UniProt ID | O60240 / PLIN1_HUMAN |
| Protein Name | Perilipin-1 |
| Gene Name | Name: PLIN1 Synonyms:PERI,PLIN; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O60240 |
| PRO Name | perilipin-1 (human) |
| Definition | A perilipin-1 that is encoded in the genome of human. |
| Short Label | hPLIN1 |
| Category | organism-gene |
DAG ViewO60240 (PLIN1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T8 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T40 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S53 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y58 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S81 | Phosphorylation | P17612 (PRKACA) | score4 | HPRD PRO PhosphoSitePlus UniProt | 11751901, 24275569 | |
| T85 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S126 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S130 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S174 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S183 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S211 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S266 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
| S277 | Phosphorylation | score1 | PRO | |||
| T299 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T301 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T306 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T314 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S374 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S382 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S384 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y401 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S408 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S436 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S440 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S461 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T476 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S497 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 29688805, 24275569 | ||
| S499 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S504 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y515 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S516 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S522 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P | 29688805, 30811273 |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000048811 (hPLIN1/Phos:1) | pS81,pS277 | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S130 | N130 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S174 | A174 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S183 | G183 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| T306 | M306 | Biomuta | DOID:1319 / brain cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
| S374 | P374 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S522 | I522 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
