iPTMnet Report for O60240 (PLIN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60240 / PLIN1_HUMAN
Protein Name Perilipin-1
Gene Name Name: PLIN1
Synonyms:PERI,PLIN;
Organism Homo sapiens (Human)

PRO ID PR:O60240
DAG View
PRO Name perilipin-1 (human)
Definition A perilipin-1 that is encoded in the genome of human.
Short Label hPLIN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60240 (PLIN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T8 Phosphorylation PhosphoSitePlus
T40 Phosphorylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
Y58 Phosphorylation PhosphoSitePlus
S81 Phosphorylation HPRD   PRO   PhosphoSitePlus   UniProt 11751901, 24275569
S81 Phosphorylation P17612 (PRKACA) HPRD 11751901
T85 Phosphorylation PhosphoSitePlus
S126 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus   UniProt 24275569
S174 Phosphorylation PhosphoSitePlus   UniProt 24275569
S183 Phosphorylation PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus
S266 O-Glycosylation GlyGen 29351928
S277 Phosphorylation PRO
T299 Phosphorylation PhosphoSitePlus
T301 Phosphorylation PhosphoSitePlus
T306 Phosphorylation PhosphoSitePlus
T314 Phosphorylation PhosphoSitePlus
S374 Phosphorylation PhosphoSitePlus
S382 Phosphorylation PhosphoSitePlus   UniProt 24275569
S384 Phosphorylation PhosphoSitePlus
Y401 Phosphorylation PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus   UniProt 24275569
S440 Phosphorylation PhosphoSitePlus
S461 Phosphorylation PhosphoSitePlus
T476 Phosphorylation PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 29688805, 24275569
S499 Phosphorylation PhosphoSitePlus
S504 Phosphorylation PhosphoSitePlus
Y515 Phosphorylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
S522 Phosphorylation PhosphoSitePlus   RLIMS-P 29688805, 30811273


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048811 (hPLIN1/Phos:1) pS81,pS277 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S130 N130 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S174 A174 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S183 G183 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T306 M306 Biomuta DOID:1319 / brain cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S374 P374 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S522 I522 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]