iPTMnet Report for O60239 (SH3BP5)
Protein Information
UniProt AC / UniProt ID | O60239 / 3BP5_HUMAN |
Protein Name | SH3 domain-binding protein 5 |
Gene Name | Name: SH3BP5 Synonyms:SAB; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O60239 |
PRO Name | SH3 domain-binding protein 5 (human) |
Definition | An SH3 domain-binding protein 5 that is encoded in the genome of human. |
Short Label | hSH3BP5 |
Category | organism-gene |
O60239 (SH3BP5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K6 | Ubiquitination | score1 | PhosphoSitePlus | |||
S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
K51 | Ubiquitination | score1 | PhosphoSitePlus | |||
S55 | Phosphorylation | score1 | PhosphoSitePlus | |||
K93 | Ubiquitination | score1 | PhosphoSitePlus | |||
K99 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y101 | Phosphorylation | score1 | PhosphoSitePlus | |||
K117 | Ubiquitination | score1 | PhosphoSitePlus | |||
K133 | Ubiquitination | score1 | PhosphoSitePlus | |||
T135 | Phosphorylation | score1 | PhosphoSitePlus | |||
S137 | Phosphorylation | score1 | PhosphoSitePlus | |||
K173 | Ubiquitination | score1 | PhosphoSitePlus | |||
K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
S208 | Phosphorylation | score1 | PhosphoSitePlus | |||
K209 | Ubiquitination | score1 | PhosphoSitePlus | |||
K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
K217 | Ubiquitination | score1 | PhosphoSitePlus | |||
K226 | Ubiquitination | score1 | PhosphoSitePlus | |||
K227 | Ubiquitination | score1 | PhosphoSitePlus | |||
K235 | Acetylation | score1 | PhosphoSitePlus | |||
K235 | Methylation | score1 | PhosphoSitePlus | |||
K235 | Ubiquitination | score1 | PhosphoSitePlus | |||
K240 | Methylation | score1 | PhosphoSitePlus | |||
K240 | Ubiquitination | score1 | PhosphoSitePlus | |||
K244 | Ubiquitination | score1 | PhosphoSitePlus | |||
K248 | Ubiquitination | score1 | PhosphoSitePlus | |||
S351 | Phosphorylation | score2 | neXtProt | 15158451 | ||
S351 | Phosphorylation | P45984 (MAPK9) | score2 | neXtProt | 15158451 | |
S351 | Phosphorylation | P53778 (MAPK12) | score2 | neXtProt | 15158451 | |
S375 | Phosphorylation | score1 | PhosphoSitePlus | |||
S376 | Phosphorylation | score1 | PhosphoSitePlus | |||
K415 | Ubiquitination | score1 | PhosphoSitePlus | |||
S416 | Phosphorylation | score1 | PhosphoSitePlus | |||
S421 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 16964243 | ||
K432 | Ubiquitination | score1 | PhosphoSitePlus | |||
S439 | Phosphorylation | score1 | PhosphoSitePlus | |||
K440 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S351 | Phosphorylation | score1 | HPRD | 15158451 | ||
S351 | Phosphorylation | P45984 (MAPK9) | score1 | HPRD | 15158451 | |
S351 | Phosphorylation | P53778 (MAPK12) | score1 | HPRD | 15158451 | |
S421 | Phosphorylation | score2 | HPRD | 19413330, 18669648, 15158451, ... | ||
S421 | Phosphorylation | P45984 (MAPK9) | score2 | HPRD | 19413330, 18669648, 15158451, ... | |
S421 | Phosphorylation | P53778 (MAPK12) | score2 | HPRD | 19413330, 18669648, 15158451, ... |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S194 | Phosphorylation | score1 | HPRD | 15158451 | ||
S194 | Phosphorylation | P45984 (MAPK9) | score1 | HPRD | 15158451 | |
S194 | Phosphorylation | P53778 (MAPK12) | score1 | HPRD | 15158451 | |
S264 | Phosphorylation | score2 | HPRD | 19413330, 18669648, 15158451, ... | ||
S264 | Phosphorylation | P45984 (MAPK9) | score2 | HPRD | 19413330, 18669648, 15158451, ... | |
S264 | Phosphorylation | P53778 (MAPK12) | score2 | HPRD | 19413330, 18669648, 15158451, ... |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K99 | E99 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y101 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K133 | N133 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K209 | R209 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
K227 | E227 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K227 | N227 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
K244 | N244 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
K248 | N248 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S375 | A375 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S376 | Y376 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K415 | Q415 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |